机构：[1]Department of Neurology, First Afliliated Hospital of Kunming Medical College, Kunming 650032, Yunnan Province, China内科科室外科科室神经内科泌尿外科昆明医科大学附属第一医院云南省第一人民医院[2]Department of Neurology, First People's Hospital of Lijiang, Lijiang 671000, Yunnan Province, China云南省第一人民医院
Currently it is not well known whether apolipoprotein E (ApoE) is a genetic susceptibility factor for cerebrovascular diseases in the Chinese Naxi population. The present study detected and sequenced ApoE polymorphisms of 90 patients with cerebrovascular diseases (58 cases of cerebral infarction and 32 cases of intracerebral hemorrhage), and 50 normal people of Naxi nationality from Yunnan province, China. The populations were used to analyze the relationship of ApoE polymorphisms with cerebral infarction and intracerebral hemorrhage. Results showed an association between ApoE gene polymorphism and the onset of cerebral infarction, and a possibility that the epsilon 4 allele is a susceptibility locus for the risk of cerebral infarction. However, there was no evidence of a relationship between the ApoE gene polymorphism and cerebral hemorrhage.
基金：
Supported by：the Scientific
Research Foundation of
Yunnan Pr0vinciaI Science
and Technology Department,
Kunming MedicaI College，
No 2008CD010
第一作者机构：[1]Department of Neurology, First Afliliated Hospital of Kunming Medical College, Kunming 650032, Yunnan Province, China[*1]Department of Neurology, First Afiliated Hospital of Kunming Medical College, Kunming 650032,Yunnan Province, China
通讯作者：
通讯机构：[*1]Department of Neurology, First Afiliated Hospital of Kunming Medical College, Kunming 650032,Yunnan Province, China
推荐引用方式(GB/T 7714)：
Hong Xu,Qihong Yuan,Xijun Fan,et al.Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province[J].NEURAL REGENERATION RESEARCH.2011,6(9):712-716.doi:10.3969/j.issn.1673-5374.2011.09.013.
APA：
Hong Xu,Qihong Yuan,Xijun Fan&Guoqiang He.(2011).Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province.NEURAL REGENERATION RESEARCH,6,(9)
MLA：
Hong Xu,et al."Apolipoprotein E gene polymorphism in cerebrovascular diseases of the Chinese Naxi populations from Yunnan province".NEURAL REGENERATION RESEARCH 6..9(2011):712-716
