Postoperative recovery for patients (particularly elderly) will be commonly encountered for postoperative neurocognitive disorders. Although effort has been undertaken to better understand and prevent these disorders, little improvement has been observed, due to largely unknown mechanisms. Emerging evidence indicates that noncoding RNAs including microRNA(s), long noncoding RNA(s), and circular RNA(s) are promising biomarkers for diagnosis, prognosis, and novel pathways to reveal mechanisms of postoperative neurocognitive disorders. However, there has been little crosstalk between noncoding RNA biology and development of postoperative neurocognitive disorders. We discuss the major noncoding RNAs in mechanisms, diagnosis, risk-stratification, prognosis, and treatment in postoperative neurocognitive disorders in a novel approach.
基金：
Health and Family Planning
Commission of Yunnan Province (H-2017047), Chuncheng
Youth Top-notch Talent Support Program (2020), the
National Natural Science Foundation of China (81860208),
and Yunnan Applied Basic Research Pr o jec t s
(2018FE001(−085)).
第一作者机构：[*1]Department of Anesthesiology, Yan’an Hospital of Kunming City, Kunming 650051, China
通讯作者：
通讯机构：[*1]Department of Anesthesiology, Yan’an Hospital of Kunming City, Kunming 650051, China[*2]Department of Anesthesiology, the First Affiliated Hospital of Kunming Medical University, Kunming 650032, China
推荐引用方式(GB/T 7714)：
He Liang,Zhang Furong,Zhu Yuling,et al.Noncoding RNAs: Novel Insights into Postoperative Neurocognitive Disorders.[J].ACS CHEMICAL NEUROSCIENCE.2021,12(9):1480-1486.doi:10.1021/acschemneuro.1c00148.
APA：
He Liang,Zhang Furong,Zhu Yuling&Lu Meilin.(2021).Noncoding RNAs: Novel Insights into Postoperative Neurocognitive Disorders..ACS CHEMICAL NEUROSCIENCE,12,(9)
MLA：
He Liang,et al."Noncoding RNAs: Novel Insights into Postoperative Neurocognitive Disorders.".ACS CHEMICAL NEUROSCIENCE 12..9(2021):1480-1486
