机构：[1]Department of Urology, Yunnan Province Clinical Research Center for Chronic Kidney Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China外科科室泌尿外科昆明医科大学附属第一医院泌尿外一科泌尿外科外科科室
Background: The aim of this study was to provide a potential surgical efficacy assessment in the treatment of pelvic organ prolapse (POP). Methods: A retrospective cohort study was performed on magnetic resonance imaging (MRI) imaging data of 16 non-prolapsed (control group) and 30 preoperative and postoperative POP (case group) women from 2019 to 2021 at the First Affiliated Hospital of Kunming Medical University. MRI diagnoses and measures of the relevant anatomical points at rest were used to analyze the healthy control data and the data from POP women before and after surgery. Results: The middle vaginal-PICS line angle (78.12 degrees +/- 15.03 degrees vs. 69.35 degrees +/- 11.51 degrees, 78.12 degrees +/- 15.03 degrees vs. 61.56 degrees +/- 9.58 degrees, P<0.05) and the middle-lower vaginal angle (179.30 degrees +/- 12.96 degrees vs. 161.73 degrees +/- 10.42 degrees, 179.30 degrees +/- 12.96 degrees vs. 147.01 degrees +/- 12.20 degrees, P<0.05) in the preoperative group were significantly larger than those in the control and postoperative groups. Y-axis coordinates of the endocervical orifice (-52.39 +/- 15.63 vs. - 59.04 +/- 11.49 mm, -52.39 +/- 15.63 vs. -65.27 +/- 7.25 mm, P<0.05), posterior vaginal fornix (-34.25 +/- 13.30 vs. - 46.69 +/- 11.09 mm, -34.25 +/- 13.30 vs. -49.93 +/- 8.02 mm, P<0.05), the junction of the middle and lower vagina (-0.48 +/- 8.65 vs. -11.34 +/- 7.33 mm, -0.48 +/- 8.65 vs. -10.11 +/- 9.77 mm, P<0.05), and anterior vaginal fornix (-23.14 +/- 13.71 vs. -34.68 +/- 9.07 mm, -23.14 +/- 13.71 vs. -38.64 +/- 6.48 mm, P<0.05), as well as the x-axes of the junction of the middle and lower parts of the vagina (26.79 +/- 6.71 vs. 19.56 +/- 5.24, 26.79 +/- 6.71 vs. 17.67 +/- 5.81, P<0.05), and vaginal introitus (23.39 +/- 7.12 vs. 18.55 +/- 4.22, 23.39 +/- 7.12 vs. 19.00 +/- 4.55, P<0.05) in the preoperative group were smaller than those of the control and postoperative groups. Differences between the control and postoperative groups were not statistically significant (P>0.05). Conclusions: The current study established that the uterine-vaginal axis of POP women moved backward and downward in the coordinate system, as shown on MRI sagittal images. Further, it moved forward and upwards after surgical repair and more closely resembled that of the control group. The uterine-vaginal axis may provide an evaluation of surgical efficacy in women with POP.
基金：
National Natural
Science Foundation of China (Grant Nos. 81802548,
81860451, 81960133); the Yunnan Natural Science
Foundation (Grant No. 202001AW070001); the Yunnan
Health Training Project of High-Level Talents (Grant No.
H2018070); and the Provincial Natural Science Foundation
of Yunnan-Kunming Medical University Joint Foundation
[Grant Nos. 2019FE001(-136), 2019FE001(-005),
202001AY070001-158].
第一作者机构：[1]Department of Urology, Yunnan Province Clinical Research Center for Chronic Kidney Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China
共同第一作者：
通讯作者：
通讯机构：[1]Department of Urology, Yunnan Province Clinical Research Center for Chronic Kidney Disease, The First Affiliated Hospital of Kunming Medical University, Kunming, China[*1]Department of Urology, The First Affiliated Hospital of Kunming Medical University, 295 Xichang Road, Kunming 650032, China.
推荐引用方式(GB/T 7714)：
Wang Haifeng,Shen Jihong,Li Song,et al.The feasibility of uterine-vaginal axis MRI-based as evaluation of surgical efficacy in women with pelvic organ prolapse[J].ANNALS OF TRANSLATIONAL MEDICINE.2022,10(8):doi:10.21037/atm-22-1173.
APA：
Wang, Haifeng,Shen, Jihong,Li, Song,Gao, Zhenhua,Ke, Kunbin&Gu, Peng.(2022).The feasibility of uterine-vaginal axis MRI-based as evaluation of surgical efficacy in women with pelvic organ prolapse.ANNALS OF TRANSLATIONAL MEDICINE,10,(8)
MLA：
Wang, Haifeng,et al."The feasibility of uterine-vaginal axis MRI-based as evaluation of surgical efficacy in women with pelvic organ prolapse".ANNALS OF TRANSLATIONAL MEDICINE 10..8(2022)
