机构:[a]Department of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China中山大学附属第二医院[b]Department of Obstetrics and Gynecology, The First Affiliated Hospital of Kunming Medical University, Kunming, People’s Republic of China产科昆明医科大学附属第一医院[c]The Medical College of Georgia, Augusta, Georgia
Objective: To determine the normative cut-off score that defines hirsutism among Chinese women, and the effect of age, menstrual irregularities, and polycystic ovaries on the same. Design: Cross-sectional, population-based study. Setting: A multistage systematic cluster random sampling among 16 communities from two rural and two city regions. Patient(s): A representative sample of 2,988 women aged 20-45 years from the general population of Southern China. Intervention(s): Subjects underwent physical and ultrasound evaluations. Main Outcome Measure(s): Terminal hair growth was assessed using the modified Ferriman-Gallwey (mFG) scoring system. Result(s): An mFG score >= 5 was observed in 10% and a score of >= 2 in 25% of the subjects. Cluster analysis identified an mFG score of 5 as the cut-off value that defines abnormal terminal facial and body hair growth in a male pattern (i.e., hirsutism) in the total population; scores of 6, 5, and 4 for women aged 20-25, 26-30, and >30 years, respectively. Defined by these cut-off values, the prevalence of hirsutism in our total population was 10.5%; and decreased with increasing age: 14.4%, 10.7%, 7.9%, 3.6%, and 1.5%, respectively, in women aged 20-25, 26-30, 31-35, 36-40, and 41-45 years. Furthermore, the incidence of acne, menses irregularities, polycystic ovaries, and acanthosis nigricans were significantly increased among the hirsute women. Conclusion(s): An mFG score of 5 or greater indicates hair growth above the norm among women in the general Southern Chinese population, a cut-off value that decreases with increasing age. (Fertil Steril (R) 2011;96:792 6. (c) 2011 by American Society for Reproductive Medicine.)
基金:
Supported by the Science Technology Research Project of Guangdong
Province (2010B031600058), the Science Technology Research Project
of Guangzhou city (2010Y1-C431), the National Science Technology
Pillar Program in the Eleventh Five-Year Plan (2007BA104B00), and the
National Science Technology Research Project (81070466) in People’s
Republic of China.
第一作者机构:[a]Department of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China
通讯作者:
通讯机构:[*1]Department of Obstetrics and Gynecology, Sun Yat-Sen Memorial Hospital, Sun Yat-Sen University, Guangzhou, People’s Republic of China 510120[*2]Department of Obstetrics and Gynecology, Medical College of Georgia, Georgia Health Sciences University, Augusta, GA, 30912
推荐引用方式(GB/T 7714):
Xiaomiao Zhao,Renmin Ni,Lin Li,et al.Defining hirsutism in Chinese women: a cross-sectional study[J].FERTILITY AND STERILITY.2011,96(3):792-796.doi:10.1016/j.fertnstert.2011.06.040.
APA:
Xiaomiao Zhao,Renmin Ni,Lin Li,Yaqin Mo,Jia Huang...&Dongzi Yang.(2011).Defining hirsutism in Chinese women: a cross-sectional study.FERTILITY AND STERILITY,96,(3)
MLA:
Xiaomiao Zhao,et al."Defining hirsutism in Chinese women: a cross-sectional study".FERTILITY AND STERILITY 96..3(2011):792-796