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Polymethylated Phloroglucinol Meroterpenoids fromRhodomyrtus tomentosaand Their Antibacterial and Acetylcholinesterase Inhibitory Effects

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机构: [1]Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China [2]Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China [3]Univ Chinese Acad Sci, Beijing 100049, Peoples R China [4]Kunming Med Univ, Dept Dermatol, Affiliated Hosp 1, Kunming 650032, Yunnan, Peoples R China [5]Yunnan Univ, Sch Chem Sci & Technol, Kunming 650224, Yunnan, Peoples R China
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关键词: Rhodomyrtus tomentosa polymethylated phloroglucinol meroterpenoids antibacterial activity acetylcholinesterase inhibitory effects

摘要:
Rhotomentodiones C-E, three new polymethylated phloroglucinol meroterpenoids with diverse configurations, were isolated from the twigs and leaves ofRhodomyrtus tomentosa. Their structures and absolute configurations were established mainly by means of comprehensive spectroscopic data and electron circular dichroism (ECD) calculation. Among them, Rhotomentodione D (2) exhibited both antibacterial activity with an MIC value of 12.5 mu g/mL againstPropionibacterium acnesand AChE inhibitory activity with an IC(50)value of 22.9 mu m.

基金:

基金编号: 31970377 2019381 2018ZF005 2019ZF010 IRT-17R49 P2019-ZZ02

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出版当年[2021]版:
大类 | 4 区 环境科学与生态学
小类 | 4 区 生化与分子生物学 4 区 化学综合
最新[2023]版:
大类 | 3 区 化学
小类 | 3 区 化学:综合 4 区 生化与分子生物学
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出版当年[2020]版:
Q3 CHEMISTRY, MULTIDISCIPLINARY Q4 BIOCHEMISTRY & MOLECULAR BIOLOGY
最新[2023]版:
Q3 BIOCHEMISTRY & MOLECULAR BIOLOGY Q3 CHEMISTRY, MULTIDISCIPLINARY

影响因子: 最新[2023版] 最新五年平均 出版当年[2020版] 出版当年五年平均 出版前一年[2019版] 出版后一年[2021版]

第一作者:
第一作者机构: [1]Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China [2]Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China [3]Univ Chinese Acad Sci, Beijing 100049, Peoples R China
通讯作者:
通讯机构: [1]Chinese Acad Sci, State Key Lab Phytochem & Plant Resources West Ch, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China [2]Chinese Acad Sci, Yunnan Key Lab Nat Med Chem, Kunming Inst Bot, Kunming 650201, Yunnan, Peoples R China
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