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Advances in the Study of the Ubiquitin-Editing Enzyme A20.

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机构: [1]Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, China
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关键词: ubiquitination ubiquitin-editing enzyme A20 inflammatory response apoptosis necroptosis pyroptosis autophagy

摘要:
Ubiquitin modification is a common post-translational protein modification and an important mechanism whereby the body regulates protein levels and functions. As a common enzyme associated with ubiquitin modification, the ubiquitin-editing enzyme A20 may be closely associated with the development of numerous pathological processes through its different structural domains. The aim of this paper is to provide an overview of the following: advances in ubiquitination research, the structure and function of A20, and the relationships between A20 and immune inflammatory response, apoptosis, necroptosis, pyroptosis, and autophagy.Copyright © 2022 Bai, Huo, Li and Shao.

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出版当年[2023]版:
大类 | 2 区 医学
小类 | 2 区 药学
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大类 | 2 区 医学
小类 | 2 区 药学
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Q1 PHARMACOLOGY & PHARMACY
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Q1 PHARMACOLOGY & PHARMACY

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第一作者机构: [1]Department of Anesthesiology, First Affiliated Hospital of Kunming Medical University, Kunming, China
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