Two newly discovered natural derivatives of benzamide, O-Ethyltembamide (1) and N-[(Z)-2-(4Methoxyphenyl)vinyl]benzamide(2), together with four known compounds, hortiamide (3), N-[(E)-2-(4-Methoxyphenyl)vinyl] benzamide (alatamide) (4), dihydroaltamide (5) and tembamid (6), were isolated from the barks of of Zanthoxylum myriacanthum var. pubescens (Huang) Huang. Their structures were determined on the basis of spectral data. The anti-inflammatory activity of the isolated compounds (1-6) were scanned against NO production in LPS-activated RAW 264.7 macrophages by MTS assay, however no significant activities were observed. [Graphical Abstract]
基金:
Yunnan Fundamental Research Projects [202101AT070057]; National Natural Science Foundation of China [82170550]
第一作者机构:[1]Kunming Med Univ, Affiliated Hosp 1, Yunnan Inst Digest Dis, Dept Gastroenterol, Kunming, Peoples R China
共同第一作者:
通讯作者:
通讯机构:[2]Yunnan Agr Univ, Coll Sci, Kunming, Peoples R China[3]Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Use, Xishuangbanna Trop Bot Garden, Xishuangbanna 666303, Peoples R China
推荐引用方式(GB/T 7714):
Liu Xiaolin,Fan Qingfei,Luo Juan,et al.Derivatives of benzamide of the extracts from the bark of Maqian (Zanthoxylum myriacanthum var. pubescens)[J].NATURAL PRODUCT RESEARCH.2023,doi:10.1080/14786419.2023.2266105.
APA:
Liu, Xiaolin,Fan, Qingfei,Luo, Juan&Miao, Yinglei.(2023).Derivatives of benzamide of the extracts from the bark of Maqian (Zanthoxylum myriacanthum var. pubescens).NATURAL PRODUCT RESEARCH,,
MLA:
Liu, Xiaolin,et al."Derivatives of benzamide of the extracts from the bark of Maqian (Zanthoxylum myriacanthum var. pubescens)".NATURAL PRODUCT RESEARCH .(2023)