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Derivatives of benzamide of the extracts from the bark of Maqian (Zanthoxylum myriacanthum var. pubescens)

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机构: [1]Kunming Med Univ, Affiliated Hosp 1, Yunnan Inst Digest Dis, Dept Gastroenterol, Kunming, Peoples R China [2]Yunnan Agr Univ, Coll Sci, Kunming, Peoples R China [3]Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Use, Xishuangbanna Trop Bot Garden, Xishuangbanna 666303, Peoples R China
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关键词: Zanthoxylum myriacanthum var pubescens (huang) huang derivatives of benzamide anti-inflammatory activity

摘要:
Two newly discovered natural derivatives of benzamide, O-Ethyltembamide (1) and N-[(Z)-2-(4Methoxyphenyl)vinyl]benzamide(2), together with four known compounds, hortiamide (3), N-[(E)-2-(4-Methoxyphenyl)vinyl] benzamide (alatamide) (4), dihydroaltamide (5) and tembamid (6), were isolated from the barks of of Zanthoxylum myriacanthum var. pubescens (Huang) Huang. Their structures were determined on the basis of spectral data. The anti-inflammatory activity of the isolated compounds (1-6) were scanned against NO production in LPS-activated RAW 264.7 macrophages by MTS assay, however no significant activities were observed. [Graphical Abstract]

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大类 | 3 区 化学
小类 | 3 区 应用化学 4 区 药物化学
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出版当年[2023]版:
Q3 CHEMISTRY, APPLIED Q3 CHEMISTRY, MEDICINAL
最新[2023]版:
Q3 CHEMISTRY, APPLIED Q3 CHEMISTRY, MEDICINAL

影响因子: 最新[2023版] 最新五年平均 出版当年[2023版] 出版当年五年平均 出版前一年[2022版]

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第一作者机构: [1]Kunming Med Univ, Affiliated Hosp 1, Yunnan Inst Digest Dis, Dept Gastroenterol, Kunming, Peoples R China
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通讯机构: [2]Yunnan Agr Univ, Coll Sci, Kunming, Peoples R China [3]Chinese Acad Sci, CAS Key Lab Trop Plant Resources & Sustainable Use, Xishuangbanna Trop Bot Garden, Xishuangbanna 666303, Peoples R China
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